When isolated from clinical specimens, nondiphtherial Corynebacteria, such as Corynebacterium striatum, Corynebacterium amycolatum. ABSTRACT. We describe an unusual cluster of Corynebacterium striatum infections in 21 patients with chronic obstructive pulmonary disease (COPD) admitted. Objective: To evaluate the clinical significance of and describe factors associated with Corynebacterium striatum infection. Methods: A.

Author: Guramar Gozilkree
Country: Serbia
Language: English (Spanish)
Genre: Health and Food
Published (Last): 15 November 2010
Pages: 93
PDF File Size: 8.30 Mb
ePub File Size: 5.91 Mb
ISBN: 329-6-20613-504-9
Downloads: 55424
Price: Free* [*Free Regsitration Required]
Uploader: JoJokree

International Journal of Systematic Bacteriology. XbaI digestion of the 63 C. Case Reports in Infectious Diseases. Multidrug-resistant, extensively drug-resistant and pandrug-resistant bacteria: Three of the conserved signature proteins have homologs found in the genus Dietziawhich is believed to be the closest related genus to Corynebacterium.

In conclusion, this study highlights the relevance of C. The clonal relationships among C.

Corynebacterium striatum Bacteremia Associated with a Catheter-Related Blood Stream Infection

Her vital signs were unstable; hence, she was immediately admitted to the intensive care unit ICU. Ishiwada N, et al.

No bacteria species could be identified at this time. Mutations in gyrA were identified by aligning sequences of resistant isolates to the sequence of C.

Corynebacterium striatum: a diphtheroid with pathogenic potential.

They are widely distributed in nature in the microbiota of animals including the human microbiota and are mostly innocuous, most commonly existing in commensal relationships with their hosts. Aminoglycosides are used as complementary antibiotics to treat serious infections caused by diphtheroids.


Enzymatic inactivation of the antibiotic molecule is the most prevalent in the clinical setting. High frequency of macrolide resistance mechanisms in clinical isolates of Corynebacterium species.

Multidrug-resistant Corynebacterium striatum bacteremia: Immunity in an infant population in the City of S. All authors reviewed and approved the manuscript. This is an open access article distributed under the Creative Commons Attribution Licensewhich permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Comparative analysis of corynebacterial genomes has led to the identification of several conserved signature indels which are unique to the genus.

The MIC 90 values of vancomycin, daptomycin and linezolid were in the range 0. Campanile F, et al. Successful treatment of Corynebacterium striatum endocarditis with daptomycin plus rifampin.

Unlike gram-negative bacteria, the gram-positive Corynebacterium species lack lipopolysaccharides that function as antigenic endotoxins in humans.

The higher level of moxifloxacin resistance in our strains suggest the existence of a resistance mechanism additional to mutations in gyrA. Received Feb 7; Accepted Aug 4. There are several reports of C. Corynebacterium striatum bacteremia associated with central venous catheter infection. Tobramycin was also very active 56 isolates were susceptible.

Corynebacteria grow slowly, even on stiatum media. Journal of Applied Bacteriology. Corynebacterium striatum pneumonia in an HIV patient.

Emergence of multidrug-resistant Corynebacterium striatum as a nosocomial pathogen in long-term hospitalized patients with underlying diseases. Clinical microbiology of Coryneform bacteria. Gomila M, et al.


Multidrug-resistant Corynebacterium striatum associated with increased use of parenteral antimicrobial drugs. Ten out of 20 carried erm X plus the erm B gene.

Corynebacterium – Wikipedia

Gram-positive bacilli were detected from two different blood corynebactrrium samples on day 67 of admission. Acquired antibiotic resistance genes: The presence of aminoglycoside modifying enzyme AME genes common in Corynebacterium spp.

Introduction Corynebacterium species are widely distributed in the environment and in the microbiota of humans and animals. Clonal multidrug-resistant Corynebacterium striatum within a nosocomial environment, Rio de Janeiro, Brazil.

Amplification and sequencing of genes related to struatum The presence of aminoglycoside modifying enzyme AME genes common in Corynebacterium spp. Thus, fluoroquinolone resistance emerged in clinical isolates of C. Luna VA, et al. Boltin D, et al. Thus, several outbreaks of clonal multidrug-resistant C. Otsuka Y, et al.

This corymebacterium highlights the high prevalence of multi-resistant strains and resistance genes among the C. Three strains had a mutation at amino acid codon Ser that changes this amino acid for Tyr or Phe. PCR reactions were performed as previously described Yoo G, et al. They may also appear elliptical. Single mutations in the residue Ser or in the residue Asp described by Sierra et al.

A case report and review.