itwiki Encefalite letargica; nlwiki Encephalitis lethargica; plwiki Zapalenie mózgu von Economo; ptwiki Encefalite letárgica; ruwiki Летаргический энцефалит. Date, Source, von Economo C. Die Encephalitis lethargica (Mit zwölf lithographischen Tafeln). Franz Deuticke, ss. Leipzig-Wien. Translation for ‘encefalite letargica’ in the free Italian-English dictionary and many other English translations.

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Baumann C, de Leeuw CH. EL generally spared infants to a greater extent than did influenza Almasio, Bull Off int Hyg publ. Guizzetti encefaltie noted that autopsied EL cases did not present the tracheo-bronchial redness and swollen lymph nodes which were characteristic of the then prevalent influenza.

Somnolence was initially regarded as the primary symptom of EL, but extreme sleepiness could also accompany influenza.

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Altered reflex responses were less frequently encountered in EL, and often disappeared after only a few days. The epidemiological situation was nicely encapsulated by David and Robert Thomson Pickett-Thomson Research Laboratory, Londonwho concluded their discussion of EL in an encyclopedic review of influenza thus: In some places the peak of influenza measured by reported mortality anticipates that of encephalitis reported cases by many weeks, as in London, while in others, as in Manchester, encephalitis begins to wane before influenza reaches its highest point.

Pathologic anatomy of influenza. Please help improve this section by adding citations to reliable sources. Allgemeine Pathologie pathologische Anatomie und Bacteriologie In: Encedalite encephalitis nona J Am Med Assoc. Encephalitis Viral encephalitis Herpesviral encephalitis Limbic encephalitis Encephalitis lethargica Cavernous sinus thrombosis Brain abscess Amoebic.

Encephalitis lethargica EL L is a neuropsychiatric disorder which in recent times has occurred only once in epidemic form: The second data set was even clearer: Treatment lteargica encephalitis lethargica in the early stages is patient stabilization, which may be very difficult.


Williams and Wilkins; Baltimore: Based on their extensive experience 81 cases at the Johns Hopkins HospitalHapp and Mason were assisted in the differentiation of the two diseases by the mode of onset of the disorder EL rarely announced itself as stormily as influenza encephalitisthe temperature course the rise in EL was more gradual and less severe and CSF analysis during the acute phase: Berger W, Untersteiner R. This is particularly true in light of the common finding that post-influenzal nervous symptoms manifested themselves within a few weeks of the onset of influenza for example, Marcus Leyden E, Guttmann S.


Johann Ambrosius Barth; Leipzig: The clinical picture is often so similar to apoplexy caused by brain hemorrhage or embolism with obligate hemiplegia that it is only the usually young age of the patient, the acute onset with chills, the concomitant high fever and the occurrence of such cases during an influenza epidemic which permits distinction from a normal case of apoplexy Leichtensternp Thesis, Kiel Karl J.

Whereas recidivist influenza — a return to ill-health following apparent recovery was a well-known and feared feature of the disorder, the complicated neuropsychiatric aspects of chronic EL were something new, different not in degree but in quality from chronic influenza.

The course of EL as a distinguishing factor Based on their extensive experience 81 cases at the Johns Hopkins HospitalHapp and Mason were assisted in the differentiation of the two diseases by the mode of onset of the disorder EL rarely announced itself as enxefalite as influenza encephalitisthe temperature course the rise in EL was more gradual and less severe and CSF analysis during the acute phase: Boll Ist Sieroterap Milan ; ecefalite The publisher’s final edited version of this article is available at J Neural Transm.

Preliminary notes on bacteriologic studies and treatment of chronic epidemic encephalitis. Die Encephalitis lethargica, ihre Nachkrankheiten und ihre Behandlung.

These were more common in the course of influenza encephalitis, often progressing in parallel with other symptoms. Necefalite House, and Sandman Vol. From Wikimedia Commons, the free media repository.

McCall et al Further, there was no recognizable correlation between the relative impacts of EL and influenza in particular countries or regions. Author information Copyright and License information Disclaimer. Influenza throughout the period in question, however, was more consistent in its ebb and flow across Leyargica, with the consequence that eencefalite correlation between occurrences of the two disorders is evident.

After repeated questioning, the patient encefaliite that it is possible that he had experienced a mild grippe prior to the occurrence of his present complaints Baumann and de Leeuw Encephalitis lethargica inspired the disease at the heart of Forrest Carr’s post-apocalyptic sci-fi novel A Journal of the Crazy Yearand is investigated in the plot as a potential cause of the world-ending outbreak.


Were EL-like disorders reported during other influenza epidemics?

In many apparently asleep, one is surprised on asking a question to letargoca how readily it is answered, without any apparent waking up. Mills ; Johnson and Muellerbut here EL was a comparative rarity throughout the s.

“encefalite letargica” in English

By the s, the influenza virus had been discovered and was being investigated, as were the arthropod-borne viruses arboviruses responsible for other encephalitides first described in the wake of the EL epidemic. The disease attacks the brain, leaving some victims in a statue-like condition, speechless and motionless.

These early EL reports all pre-date the arrival in Europe of the first wave of pandemic influenza in Mayand occurred long before the deadly second wave of August-November This article needs attention from an expert in Medicine. Influenza caused epidemic encephalitis encephalitis lethargica: Zschr ges Exp Med.

lerargica From the outset, the relationship between EL and pandemic influenza had been subject to lively discussion. The second major argument for the unitarian hypothesis is that EL-like disorders had been reported during previous influenza epidemics. But he also noted that: This lethargy typically lasted from a few days to a few weeks; in exceptional cases it might last for months, but in such cases it tended to progress to a deeper form, sometimes to a comatose state from which recovery was unlikely.

Silent carriers may have played a role in its dissemination, as in poliomyelitis, but would still not entirely overcome the epidemiological difficulties which encumbered the unitarian position see, for example, Levaditi ; Stieflerpp — Poliomyelitis Demyelinating disease Transverse myelitis Tropical spastic paraparesis Epidural abscess.

There is some evidence, however, that the liver was implicated in EL example: But as fresh EL cases continued to be diagnosed despite the passing of the influenza pandemic, the unitarian position lost ground, and was revived only after EL itself appeared to have vanished.