TRALI: transfusion related acute lung injury. vegetales pueden brindar contra las enfermedades degenerativas, como cáncer y enfermedades cardiovascular, . 4 Within the critical care literature, significant blood transfusion can cause transfusion related acute lung injury (TRALI) which is similar to PGD in clinical and. Lesion pulmonar aguda producida por transfusion sciencedirect. This is the first case of transfusionrelated acute lung injury trali, associated with acute.

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Auscultation has discrete changes that do not explain the reduction in oxygen saturation and radiographic images 5. Hypotension can be treated with the administration of fluids or, in refractory cases, vasopressors. On the other hand, TRALI is common and notoriously underestimated due to the diversity of diagnostic hypotheses, justifying the dissemination of the knowledge of this disorder, especially in our country, where the anesthesiologist is involved directly in blood transfusions.

Data regarding the patient, as well as ejfermedad complication resulting from the transfusion, were recently included in the data bank of a health agency. If the patient is intubated and under mechanical ventilation it might present with difficulty to ventilate, increased endotracheal pressure, and abrupt reduction in blood pressure.

This explains the need to contact the blood bank to take proper measures regarding other blood products involving the donor that might be still in storage. Approximately 20 minutes after admission to the PARR, the results of her blood work revealed Hb 8 mg.

The patient showed progressive improvement and was discharged from the Enfermeddad 36 hours after her admission to the unit. Am Rev Respir Dis, ; Since most transfusions are surgery-related 6if transfusion is done during the surgery, this disorder may develop early, hindering the diagnosis, which might not even be made. Blood for arterial blood gases was drawn and a bed in the intensive care unit was requested ICU. The last hypothesis was considered more likely and, therefore, mg of hydrocortisone IV was administered and the blood bank was contacted traali make the proper arrangements with the donor.


Therefore, the knowledge of this disorder and its dissemination, especially in our country, is important. Dyspnea is another characteristic symptom of this reaction, se usually develop over a few minutes due to acute pulmonary edema leading to reduction in arterial oxygen saturation and in many cases cyanosis.

The chest X-ray had improved, with residual basilar opacities Figure 2. In the present case, since the patient was awake, she developed cough and eliminated frothy material through the mouth, which indicated the diagnosis of pulmonary edema.

However, since reliable data on its epidemiology in Brazil are not available, the difficulty to diagnose, varied clinical presentation, and absence of specific laboratory data, case reports are wnfermedad. Laboratory exams showed Hb On auscultation, she had rare crackles and rales bilaterally, more prominent on the bases. Trali transfusion related acute lung injury is characterized by acute respiratory distress and noncardiogenic lung oedema developing during, or within 6 hours of transfusion.

Since reliable data on its epidemiology in Brazil are not available, the difficulty to diagnose, varied clinical presentation, and absence of specific laboratory data, case reports are important.

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Diuretics are not recommended when volume overload is not present. During the pre-anesthetic evaluation, done the day before, the patient stated she had undergone two breast surgeries under general anesthesia for removal of nodes without intercurrences. Enfermedad injerto contra huesped asociada a transfusion.

However, the clinical presentation is characterized by a constellation of non-specific signs and symptoms common to several disorders, making for a difficult differential diagnosis.

Auscultation revealed improvement of the breath sounds, with rare crackles in the bases. dd


The present case report emphasized the importance of judicious care when transfusing blood, since the inherent risks go beyond the transmission of viral diseases, the most feared complication although rare in countries with elevated human development index. It is a relatively rare, lifethreatening clinical syndrome characterized by acute respiratory failure and noncardiogenic pulmonary edema during or following a blood transfusion.

A transfusionrelated acute lung injury, also known as trali, is a very rare complication related to transfusion of blood components even though, it is consider the main cause of mortality when we refer to adverse outcomes enfwrmedad this procedure, presenting mortality rates. Enfermevad, the patient developed coughing productive of frothy secretion approximately 90 minutes after the transfusion.

D surgery evolved without intercurrences, the patient remained hemodynamically stable, with effective urine output, and intraoperative losses were compensated by the administration of 2, mL of NS and mL of hetastarch.

Immediately after the transfusion of one unit of packed red blood cells in the post-anesthetic recovery room, she developed respiratory failure, which did not require reintubation. There, treatment with mg of hydrocortisone IV every eight hours continued, along with ipratropium bromide and fenoterol.

Acute respiratory distress syndrome – ERS

At the end of the surgery, blood for the determination of Hb and MCV was drawn, and the patient was extubated without intercurrences.

Among the differential diagnoses the possibility of acute lung injury ALI by sepsis or bronchoaspiration, and due to the cause-effect relationship, transfusion-related acute lung injury TRALI was included.

Fluid administration presupposes the exclusion of fluid overload and cardiogenic pulmonary edema.