ERYTHROMYCIN LACTOBIONATE PACKAGE INSERT PDF

Erythromycin Lactobionate 1g Powder for Solution for Infusion – Summary of Product Characteristics (SmPC) by ADVANZ Pharma. Erythromycin Lactobionate I.V. is a sterile presentation of erythromycin. It is not When administering the product by intermittent infusion do not use solution strengths greater than . includes any possible side effects not listed in this leaflet. Intravenous infusion of mg of erythromycin lactobionate at a constant rate physiologically concentrated or in situations where high dosage of drug can be.

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Skin and soft tissue infections: Even though it may be rare, some people may have very bad and sometimes deadly side effects when taking a drug. Sign Up Log In Cancel.

Erythromycin Lactobionate – I.V.

Eryfhromycin significantly alters the metabolism of terfenadine, astemizole and pimozide when taken concomitantly. Lower Respiratory Tract infections: Erythromycin antagonises the action of clindamycin, lincomycin and chloramphenicol. Upper Respiratory Tract infections: Benzyl alcohol may be added as a preservative.

There have been reports that maternal macrolide antibiotics exposure within 7 weeks of delivery may be associated with a higher risk of infantile hypertrophic pyloric stenosis IHPS.

Use Erythromycin Lactobionate – I. Gram positive bacteria – Listeria monocytogenes, Corynebacterium diphtheriae as an adjunct to antitoxinStaphylococci spp, Streptococci spp including Enterococci. Rare reports of rhabdomyolysis have been reported in patients taking these drugs concomitantly. To view the changes to a medicine you must sign up and log in. Bolus injection is not recommended. Bronchitis ciprofloxacinamoxicillindoxycyclineazithromycinAugmentinMore Physicians should be aware that reappearance of the allergic symptoms may occur when symptomatic therapy is discontinued.

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For further details please see section 6. Dosage Information in more detail. If you think there has been an overdose, call your poison control center or get medical care right away.

These are not all of the side effects that may occur. The same applies for streptomycin, tetracyclines and colistin. There have been reports of infantile hypertrophic pyloric stenosis IHPS occurring in infants following erythromycin therapy.

Marketing authorisation number s 9. Side effects in more detail. Since erythromycin may be used in the treatment of conditions in infants which are associated with significant mortality or morbidity such as pertussis or chlamydiathe benefit of erythromycin therapy needs to be weighed against the potential risk of developing IHPS.

Benzyl alcohol has been reported to be associated with a fatal ‘Gasping Syndrome’ in premature infants. Parents should be informed to contact their physician if vomiting or irritability with feeding occurs.

For Intermittent Infusion of 1 gram dose: GranulesErycWe comply with the HONcode standard for trustworthy health information – verify here. Erythromycin is contraindicated with ergotamine and erythgomycin. Erythromycin has been reported to cross the placental barrier in humans, but foetal plasma levels are generally low.

Qualitative and quantitative composition 3. Read all information given to you. This provides a 0.

Erythromycin Lactobionate 1g Powder for Solution for Infusion

Clostridium difficile-associated diarrhoea CDAD has been reported with use of nearly erythromycn antibacterial agents including erythromycin, and may range in severity from mild diarrhoea to fatal colitis. General disorders and administration site lactobinate Rhabdomyolysis with or without renal impairment has been reported in seriously ill patients receiving erythromycin concomitantly with statins.

There are no adequate and well-controlled studies in pregnant women. The infusion should be completed within 8 hours of preparation to ensure potency. Tell your doctor or get medical help right away if you have any of the following signs or symptoms that may be related to a very bad side effect:.

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Erythromycin Lactobionate – I.V. Information –

Continuous infusion of this medicine is preferred due to the slower infusion rate and lower concentration of erythromycin; however, intermittent infusion at intervals not greater than every six hours is also effective. Tell your doctor and pharmacist about all of your drugs prescription or OTC, natural products, vitamins and health problems. Have you considered biologics for your severe psoriasis? Active ingredient erythromycin lactobionate. As a result of this plasma levels of active steroid may decrease.

Erythromycin should not be used during and two weeks after treatment with CYP3A4 inducers. Following intravenous infusion, erythromycin is widely distributed throughout body tissues, including lung tissues.

Elevated cisapride levels have been reported in patients receiving erythromycin and cisapride concomitantly. No special dosage recommendations. If you have questions about side effects, call your doctor. Recommended Administration Bolus injection IV push is contraindicated Continuous infusion of this medicine is preferred due to the slower infusion rate and lower concentration of erythromycin; however, intermittent infusion at intervals not greater than every six hours is also effective.

Drugs that induce CYP3A4 such as rifampicin, phenytoin, carbamazepine, phenobarbital, St John’s Wort may induce the metabolism of erythromycin.