FOSPHENYTOIN PRESCRIBING INFORMATION PDF

This resource may include information that has not been approved by the US Food and Drug Administration. For full prescribing information, including. Fosphenytoin official prescribing information for healthcare professionals. Includes: indications, dosage, adverse reactions, pharmacology and more. Medscape – Epilepsy dosing for Cerebyx (fosphenytoin), frequency-based adverse contraindications, pregnancy & lactation schedules, and cost information. be expressed as phenytoin sodium equivalents (PE) when prescribing; There is.

Author: Yojar Nakazahn
Country: Austria
Language: English (Spanish)
Genre: History
Published (Last): 1 November 2007
Pages: 95
PDF File Size: 2.75 Mb
ePub File Size: 15.2 Mb
ISBN: 772-4-81277-832-8
Downloads: 13655
Price: Free* [*Free Regsitration Required]
Uploader: Faegore

Pro-Epanutin is a clear, colourless to pale yellow, sterile fosphhenytoin buffered with trometamol adjusted to pH 8. Cannabidiol The metabolism of Fosphenytoin can be decreased when combined with Cannabidiol.

Metocurine The risk or severity of adverse effects can be increased when Fosphenytoin is combined with Metocurine.

FOSPHENYTOIN SODIUM Injection mg PE in 2ml Vial mg PE in 10 ml Vial | Mylan

Candesartan The metabolism of Fosphenytoin can be decreased when combined with Candesartan. Total exchange transfusion has been used in the treatment of severe intoxication in children. Table 3 includes commonly occurring drug interactions that affect phenytoin the active metabolite of Fosphenytoin Sodium Injection concentrations.

Formaldehyde is subsequently converted to formate, which is in turn metabolized via a folate dependent mechanism. There have been several reported cases of malignancies, including neuroblastoma, in children whose mothers received phenytoin during infformation. The physician should advise the patient to discontinue treatment if the rash appears.

In all cases of lymphadenopathy, follow-up observation for an extended period is indicated and every effort should be made to achieve seizure control using alternative antiepileptic drugs.

Fish oil The metabolism of Fosphenytoin can be decreased when combined with Fish oil. Ixabepilone The metabolism of Ixabepilone can be increased when combined with Fosphenytoin. Acalabrutinib The metabolism of Fosphenytoin can be decreased when combined with Acalabrutinib.

  BALAAM AND DILLMAN PDF

Maprotiline The risk or severity of adverse effects can pescribing increased when Maprotiline is combined with Fosphenytoin. Hemodialysis can be considered since phenytoin the active metabolite of Fosphenytoin Sodium Injection is not completely bound to plasma proteins.

Pro-Epanutin Concentrate for Infusion / Solution for Injection

No effects on fertility were observed in males. Table 7 displays dosing information for status epilepticus maintenance dose in children.

Crizotinib The metabolism of Fosphenytoin can be decreased when combined with Crizotinib. Adinazolam The metabolism of Fosphenytoin can be decreased when combined with Adinazolam. Hydrocortisone acetate The metabolism of Fosphenytoin can be increased when combined with Hydrocortisone acetate. Desogestrel The metabolism of Fosphenytoin can be decreased when combined with Desogestrel. Doravirine The metabolism of Fosphenytoin can be decreased when combined with Doravirine.

Gallopamil The metabolism of Fosphenytoin can be decreased when combined with Gallopamil. Guanabenz The metabolism of Guanabenz can be increased when combined with Fosphenytoin. Mean total phenytoin half-life values Anisodamine The metabolism of Anisodamine can be increased when combined with Fosphenytoin.

Midazolam Informatiob metabolism of Midazolam can be increased when combined with Fosphenytoin. Aluminium phosphate Aluminium phosphate can cause a decrease in the absorption of Fosphenytoin resulting in fosphneytoin reduced serum concentration and potentially a decrease in efficacy.

Ibipinabant The risk or severity of adverse effects can be increased when Ibipinabant is combined with Fosphenytoin. Total exchange transfusion has been used in the treatment of severe intoxication in children.

Fosphenytoin – FDA prescribing information, side effects and uses

Haemorrhagic syndrome has been reported in neonates born from epileptic mothers receiving phenytoin. Meloxicam The metabolism of Fosphenytoin can be decreased when combined with Meloxicam. There have been several reported cases rpescribing malignancies, including neuroblastoma. This information is intended for use by health professionals. Allopurinol The metabolism of Fosphenytoin can be decreased when combined with Allopurinol.

HIGHLIGHTS OF PRESCRIBING INFORMATION

innformation In view of isolated reports associating phenytoin the active metabolite of Fosphenytoin Sodium Injection with exacerbation of porphyria, caution should be exercised in using Fosphenytoin Sodium Injection in patients suffering from this disease. Lisuride The metabolism of Fosphenytoin can be decreased when combined with Lisuride. In acute overdosage the possibility of the use of other CNS depressants, including alcohol, should be borne in mind.

  BEYOND THE APEX GT6 PDF

Indometacin The metabolism of Fosphenytoin can be decreased when combined with Indomethacin. Kitasamycin The metabolism of Fosphenytoin can be decreased when combined informatioj Kitasamycin. Lestaurtinib The metabolism of Fosphenytoin can be decreased when combined with Lestaurtinib.

Metahexamide The metabolism of Fosphenytoin can be decreased when combined with Metahexamide. When appropriate, counsel pregnant women and women of childbearing potential about alternative therapeutic options. As non-emergency therapy, intravenous Fosphenytoin Sodium Injection should be administered more slowly. Gemfibrozil The metabolism of Fosphenytoin can be decreased when combined with Gemfibrozil. Instruct patients to notify their physician if they become pregnant or intend to become pregnant during therapy, and to notify their physician if they are breastfeeding or intend to breastfeed during therapy [see Use in Specific Populations 8.

In patients with acute hepatotoxicity, fosphenytoin should be immediately discontinued and not re-administered. Nausea, vomiting, lethargy, tachycardia, bradycardia, asystole, cardiac arrest, hypotension, syncope, hypocalcemia, metabolic acidosis, and death have been reported in cases of overdosage with fosphenytoin.

Bucindolol The metabolism of Bucindolol can be increased when combined with Fosphenytoin. Apalutamide The serum concentration of Fosphenytoin can be increased when it is combined with Apalutamide. Flunisolide The metabolism of Fosphenytoin can be increased when combined with Flunisolide.

An inforamtion in seizure frequency may occur during pregnancy because of altered phenytoin pharmacokinetics. Antiepileptic drugs should not be abruptly discontinued because of the possibility of increased seizure frequency, including status epilepticus.