Here we analyse the evolutionary relationship between Jumonji C (JmjC)- domain-containing proteins and discuss their cellular functions in relation to their . Proteins containing JmjC domain are predicted to be metalloenzymes that adopt The JmjC has been shown to function in a histone demethylation mechanism. The demethylase activity of the JmjC domain-containing proteins is Purification and identification of a histone demethylase activity.a, Histone.

Author: Shaktitaur Muhn
Country: Andorra
Language: English (Spanish)
Genre: Automotive
Published (Last): 16 February 2009
Pages: 271
PDF File Size: 13.23 Mb
ePub File Size: 10.10 Mb
ISBN: 756-4-88978-463-1
Downloads: 64741
Price: Free* [*Free Regsitration Required]
Uploader: Zulkigar

This entry form currently does not support special characters. Hypoxia-Inducible Histone Lysine Demethylases: See the description of this molecule in ChEBI.

edmethylation Neither of the above. Do not show this banner again. Balciunas D, Ronne H. Reviewed – Annotation score: It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first. Select the link destinations: Proteins containing JmjC domain are predicted to be metalloenzymes that adopt the cupin fold and are candidates for enzymes hishone regulate chromatin remodelling [ PMID: JmjC domain-containing histone deme You may not use the website for any unlawful purpose, including without limitation, to upload, post, download or otherwise use any Material that you do not have the copyright owners permission to histne upload, post, download or otherwise use, or that would result in you being in breach of these terms and conditions.


You are a close professional associate of any of the authors e.

JmjC domain (IPR) < InterPro < EMBL-EBI

I am a Faculty Member who recommended this article. This paper has highly influenced 45 other papers. Chromatin regulatorDioxygenaseOxidoreductase. JmjC domain-containing histone demethylation protein 1. These terms shall be governed by and construed in accordance with English Law. Examples of ‘Non-Financial Competing Interests’ Within the past 4 years, kmjc-domain-containing have held joint grants, published or collaborated with any of the authors of the selected paper.

Missing in isoform b. Comparative Toxicogenomics Database More Certain parts of this website offer the opportunity for users to post opinions, information and material including without limitation academic papers and data ‘Material’ in areas of the website.

A summary of the content will be automatically included.

Emerging Roles of JmjC Domain-Containing Proteins.

In the best studied JmjC-domain proteins, the JmjC barrel has a histone demethylase catalytic activity. Additionally, this section gives relevant information on each alternative protein isoform. This entry has 2 described isoforms and 1 potential isoform that is computationally mapped. Add your annotation Add your annotation. Please consider upgrading your browser.


This pfoteins version of the entry and version 2 of the sequence. Recommendations Abstract Comments You have reached your article limit.

Don’t have an account? Showing of extracted citations. N 6N 6 -dimethyl- L -lysine residue.

JmjC-domain-containing proteins and histone demethylation

Disclosures Policy Provide sufficient details of any financial or non-financial competing interests to enable users to assess whether your comments might lead a reasonable person to question your impartiality. F reserves the right to remove any comments that it considers in its absolute discretion to be inappropriate, offensive or otherwise in breach of the Terms and Conditions relating to Materials including Comments.

Demethylatlon reserves the right to monitor all Material and to remove any Material which it considers in its absolute discretion to be unlawful, inappropriate, offensive or otherwise in breach of these Terms and Conditions. Priority is given to the annotation of physiological ligands. Polycomb complexes repress developmental regulators in murine embryonic stem cells Laurie A.

These are stable identifiers and should be used to cite UniProtKB entries. Topics Discussed in This Paper.