Non-Hodgkin lymphoma (also known as non-Hodgkin’s lymphoma, NHL, or lymphoma) is a cancer that starts in the lymphocytes, which are. Find out what you need to know about malignant lymphoma, including symptoms, treatment, and outlook. ON THIS PAGE: You will learn about how doctors describe lymphoma’s location and spread. This is called the stage. Use the menu to see other g.

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The incidence of non-Hodgkin lymphoma increases with age. If you believe you have swollen lymph nodes, make an appointment to see your doctor.

Table 2 Monomorphic small cell B-cell neoplasms commonly encountered. Pancreatic HD is extremely rare and, in almost all cases, secondary to contiguous lymph node disease [ 512 ].

Intrinsic involvement of genitourinary GU organ systems at presentation is rare [ 5 ]. A division into Hodgkin and non-Hodgkin lymphomas is used in several of the older classification systems.

In patients with known disease, the goals of imaging are staging, evaluation of response to therapy, and identification of new or recurrent disease or of complications of therapy.

A biopsy can also detect the difference between Hodgkin lymphoma and NHL, as well as their various sub-types. By using this site, you agree to the Terms of Use and Privacy Policy.

Retrieved from ” https: The patterns of small bowel involvement include solitary or multiple nodules, circumferential wall thickening Figure 21 with or without aneurysmal dilatation, and direct extension from mesenteric nodes [ 210 ]. Treatment may involve one or more of the following: This refers to determining if the cancer has spread, and if so, whether locally or to distant sites.

Some centers advocate the use of single agent rituximab in the treatment of follicular lymphoma rather than the wait and watch approach.


Several classification systems have existed for lymphoma, which use histological and other findings to divide lymphoma into different categories. Staging is carried out because the stage of a cancer impacts its prognosis malinga treatment. This is an open-access article distributed under the terms limfoms the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Author information Copyright and License information Disclaimer. Saunders Elsevier publishers; Age and poor performance status are established poor prognostic factors, as well. Leukemia and Lymphoma Society. Types of malignant lymphoma. WHO classification of tumours of haematopoietic and lymphoid tissues. Archived PDF from the original on 14 July Lymph nodes are bean-sized collections of lymphocytes and other immune system cells. The two types spread in different ways and respond differently to treatment.

HD is usually almost entirely confined to the lymph nodes [ 45 ]. Suspicion of neoplasm or specific infection is limited to patients with larger nodes, nodes in other locations, or large clusters of smaller nodes.

What Is Non-Hodgkin Lymphoma?

A year-old man with gastric lymphoma. Symptoms of malignant lymphoma. The stomach, small bowel, pharynx, large bowel, and esophagus are involved in decreasing order of frequency [ 2 ]. CT of the pelvis shows concentric thickening of small bowel loop on the right reducing its lumen arrows.

This system groups lymphomas by cell type i. Many low-grade lymphomas remain indolent for many years. In decreasing order of frequency, the spleen, liver, gastrointestinal tract, pancreas, abdominal wall, genitourinary tract, adrenal, peritoneal cavity, and biliary tract are involved. In contrast to GI adenocarcinoma, lymphoma is more likely to involve multiple and longer segments of gut and is less likely to cause bowel obstruction. Prognosis for malignant lymphoma patients.


In patients without known disease, imaging permits a provisional diagnosis. lifoma

What Is Hodgkin Lymphoma?

This is a procedure in which your doctor removes cells from a lymph node and has them examined under a microscope. The maljgna common form of testicular lymphoma is diffuse large B-cell lymphoma. After a diagnosis and before treatment, a cancer is staged. Burkitt’s lymphoma is a relatively rare and aggressive form of non-Hodgkin’s lymphoma.

Also the extent of extranodal involvement must be evaluated because it is considered prognostic [ 5 ].

What Is Non-Hodgkin Lymphoma?

Learn the different types, possible symptoms, life expectancy, and available treatment options. Enlarged lymph nodes in people with cHL usually have a small number of Reed-Sternberg cells with a lot of normal immune cells around them.

Axial abdominal CT after administration of intravenous CM reveals a large mass in spleen arrows. New England Journal of Medicine.

They’re connected to each other by a system of lymphatic vessels. Having swollen lymph nodes doesn’t necessarily mean you have lymphoma. The classification of a lymphoma can affect treatment and prognosis. The cancer cells in NLPHL are large cells called popcorn cells because they look like adakahwhich are variants of Reed-Sternberg cells.

Role of immunohistochemistry in lymphoma

Immunohistology of Hodgkin lymphoma diagnostic lumfoma Lymphoma is a group of blood cancers that develop from lymphocytes a type of white blood cell. If no obvious cause can be found upon physical examination, your doctor may order blood tests or other diagnostic testing.

Axial contrast-enhanced abdominal CT demonstrates multiple hypodense lesions involving the kidneys.